Andrew Koenig, the "Growing Pains" star and son of Walter Koenig of Star Trek fame, died after - according to his father - having committed suicide, following severe depression. We do not have a birth time, so I'm going to focus on specific parts of his chart, mainly the Sun/Neptune tight square and all those Virgo planets. This is going to be a more general analysis, not only because we don't have an accurate birth time, but also because a natal chart is only a natal chart, no matter how important. What we are today is a result of all the connections our natal chart has made with the other natal charts over the years. It is still impossible to know the whole truth about a person.
I've always associated the sign of Virgo with depression, much more so than other signs. Virgo is not a fire sign, which means that it doesn't find life exciting. It's not a water sign, so it doesn't seek solace in emotional connections with other people and it's not an air sign, ready and eager to worship at the altar of knowledge. It is an earth sign, but unlike Taurus, it doesn't find meaning in bodily senses and unlike Capricorn, it doesn't aim at conquering the body and its weaknesses.
It's the sign opposite Pisces, which means that it's the sign as far away from God as possible. Virgos are not here to realize how we are all interconnected, but how different we are from each other. And they do exactly that. They tend to be critical and find fault with everything. But when you find fault with everything, you end up being alone. You are not likely to be appreciated, which can be pretty depressing.
So, what a Virgo needs is stamina and endurance and they need to learn how to handle separateness and make something useful out of it. In short, they need a healthy Saturn. Koenig has a very bad Saturn, in Aries and retrograde. Not much help, there. To top it all, Koenig has a very tight Sun/Neptune square, which contradicts the Virgo energy. Here is a man or a part of him, that hates separateness. This aspect can be equally depressing, because it can't survive without some sort of God. Only the belief that there is a God, who moves in mysterious ways, can make life bearable, because otherwise life is a disaster, a huge cosmic joke. But how can Koenig find a God with all that Virgo energy?
At the moment of his death, he was going through some very difficult outer planet transits. The Uranus opposition, which signals the middle-life crisis and the very difficult Neptune transit, forming a T-square with his natal Sun/Neptune. So, not only was he saying goodbye to his youth, but his natural tendency to view life on the earthly plane as utterly meaningless was exacerbated. Of course, this doesn't mean that suicide was his only option, a lot of people are going through similar transits with no such dramatic consequences, but, still, this is not the happiest of times.